Later, in classical times the ancient city rivalled Athens and Thebes in wealth, based on the isthmian traffic and trade. Until the mid-6th century Corinth was a major exporter of black-figure pottery to cities around the Greek world. Athenian potters later came to dominate the market. Corinth's great temple on its acropolis was dedicated to Aphrodite. According to most sources, there were more than one thousand temple prostitutes employed at the Temple of Aphrodite. Corinth was also the host of the Isthmian Games.

In the 7th century BC, when Corinth was ruled by the tyrants Cypselus and Periander, the city sent forth colonists to found new settlements: Syracuse, Ambracia, and with Corcyra, itself perhaps the site of an early Corinthian settlement, Apollonia and Anactorium.

The Romans under Lucius Mummius destroyed Corinth following a siege in 146 BC; when he entered the city Mummius put all the men to the sword and sold the women and children into slavery before he torched the city, for which he was given the cognomen Achaicus as the conqueror of the Achaean League.

While there is archeological evidence of some minimal habitation in the years afterwards, Julius Caesar refounded the city as Colonia laus Iulia Corinthiensis in 44 BC shortly before his assassination.